Find out more about the services of the Genetic Toxicology Laboratory of the Institut Pasteur de Lille
Human health, nanotechnologies and the environment. Find out more about our research areas
The genetic toxicology laboratory offers specific and custom training.
Genetic Toxicology Laboratory
Institut Pasteur de Lille
Genetic Toxicology Laboratory
Created in 1981 by Professeur Daniel Marzin, the Genetic Toxicology Laboratory of the Institut Pasteur de Lille performs on demand genetic toxicology studies to assess the genotoxic and mutagenic potential of various types of substances under strict GLP (Good Laboratory Practices) conditions. Currently directed by Doctor Sophie Simar, toxicologist, this reference laboratory is one of the largest genotoxicity research centres in France.
Boasting a broad range of areas of expertise (human health, animal health, cosmetics, chemistry, botanicals, nanotechnologies, environment, etc.) our consultants at the Genetic Toxicology Laboratory can provide expert advice concerning the choice of tests to be carried out and can interpret the test results.
News
Endocrine disruption
The laboratory offers in vitro tests for the identification of endocrine disruptors. These are tests to reveal interactions with hormone receptors (oestrogens and androgens) or with steroidogenesis: the H295R steroidogenesis test, the E-Screen test, the MDA-kb2 test...
Predictive toxicology software
The ICH M7 guideline, for the evaluation and monitoring of mutagenic impurities contained in pharmaceutical products and the limitation of their potential carcinogenic risk, recommends the use of experimental data demonstrating structure-activity relationships...
DDR Kit
Our portfolio is expanding with new tests and services: The DDR Kit or 'Multi Flow DNA Damage Repair Kit' (Litron Laboratories, USA) allows flow cytometric evaluation of the clastogenic, aneugenic and cytotoxic potential of substances in a screening context. Exposure...
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