Miniaturised genotoxicity tests
For several years, the Genetic Toxicology Laboratory of the Institut Pasteur de Lille has employed an approach to preventative assessment of the genotoxic potential of new molecules in the development phase, impurities, etc., using miniaturised methods tests.
In addition, as part of high-throughput screening, we perform the DNA Damage Response Pathway test in the laboratory.
| TESTS | DOCUMENTS |
|---|---|
| MiniAmes | Flamand et al., 2001 |
| MicroAmes | Courty et al., 2008 |
| Micronucleus in vitro on TK6 or L5178Y cells | Nesslany et al., 1999 |
| DDR in vitro (100 mg of product) on TK6 cells |
Standard tests
All standard tests can be performed by means of non-GLP screening
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